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AMETHYST Gout Clinical Research Study

Is your gout under control? AMETHYST gout clinical research study

The AMETHYST Study is exploring new options
for gout management

Join the AMETHYST Study of a possible treatment for adults with gout who still have flare-ups and cannot take allopurinol or febuxostat, or for whom intravenous (IV) uricase treatment did not help.

The AMETHYST Study is testing the effectiveness and safety of a study drug, dotinurad, at lowering serum uric acid. This is the waste product that builds up in the blood, leading to gout symptoms.

You may be able to join the
AMETHYST Study if you:

  • Are 18 to 75 years of age
  • Have been diagnosed with gout for at least 1 year
  • Still have gout flare-ups and either
    • Are unable to take allopurinol or febuxostat
    OR
    • Intravenous (IV) uricase treatment was not effective

You will need to meet other requirements to join the AMETHYST Study. Please contact us for details.

If you qualify and decide to take part, you will get:

  • The study drug, dotinurad
  • Medication to prevent gout flares
  • Study-related medical care throughout the study
  • Reimbursement for reasonable study-related expenses (travel and meals)

Please visit ClinicalTrials.gov and search NCT07535034 or contact us to find out more:

Hometown Clinical Research at 6210 Brandt Pike, Huber Heights, Ohio. Phone 937-912-1225. QR code for AMETHYST Study information.
AMETHYST Study
FYU-981-CRYS-201_Flyer_v1.0_US Eng_16MAR2026
Hometown Clinical Research, 6210 Brandt Pike, Huber Heights, Ohio. Phone 937-912-1225. Visit ClinicalTrials.gov and search NCT07535034 for additional study information.

Important Study Information

This page provides information about a clinical research study evaluating an investigational therapy. Participation is voluntary. Submitting this form does not enroll you in the study or guarantee eligibility. A member of the study team may contact you to discuss preliminary screening and provide additional study information.

Information submitted through this form will be used to respond to your inquiry and assess preliminary study eligibility in accordance with the Hometown Research Privacy Policy. This form is not the informed consent form for participation in the study.